Space Plants for Astronaut Consumption

Growing plants in space will be an essential part of sustaining astronauts during long-range missions. During the summer of 2017, three female NASA interns, have been engaged in research relevant to food production in space, and will present their projects to an all female program known as Girls in STEM camp. Ayla Grandpre, a senior from Rocky Mountain College, has performed data mining and analysis of crop growth results gathered through Fairchild Botanical Gardens program, Growing Beyond Earth. Ninety plants were downselected to three for testing in controlled environment chambers at KSC. Ayla has also managed an experiment testing a modified hydroponics known as PONDS, to grow mizuna mustard greens and red robin cherry tomatoes. Emma Boehm, a senior from the University of Minnesota, has investigated methods to sterilize seeds and analyzed the most common microbial communities on seed surfaces. She has tested a bleach fuming method and an ethanol treatment. Emma has also tested Tokyo bekana Chinese cabbage seeds from four commercial seed vendors to identity differences in germination and growth variability. Lastly, Payton Barnwell, a junior from Florida Polytechnic University has shown that light recipes provided by LEDs can alter the growth and nutrition of 'Outredgeous' lettuce, Chinese cabbage, and Mizuna. The results of her light quality experiments will provide light recipe recommendations for space crops that grown in the Advanced Plant Habitat currently aboard the International Space Station

Increasing Neff with particles in thermal equilibrium with neutrinos

Recent work on increasing the effective number of neutrino species (Neff) in the early universe has focussed on introducing extra relativistic species (`dark radiation'). We draw attention to another possibility: a new particle of mass less than 10 MeV that remains in thermal equilibrium with neutrinos until it becomes non-relativistic increases the neutrino temperature relative to the photons. We demonstrate that this leads to a value of Neff that is greater than three and that Neff at CMB formation is larger than at BBN. We investigate the constraints on such particles from the primordial abundance of helium and deuterium created during BBN and from the CMB power spectrum measured by ACT and SPT and find that they are presently relatively unconstrained. We forecast the sensitivity of the Planck satellite to this scenario: in addition to dramatically improving constraints on the particle mass, in some regions of parameter space it can discriminate between the new particle being a real or complex scalar.Comment: 10 pages, 5 figures v2 matches version to appear in JCA

Ballistic magnetoresistance in nickel single-atom conductors

Large ballistic magnetoresistance (BMR) has been measured in Ni single-atom conductors electrodeposited between microfabricated thin films. These measurements irrefutably eliminate any magnetostriction related artifacts in the BMR effect.Comment: 12 pages, 3 Figure

PHASES High Precision Differential Astrometry of delta Equulei

delta Equulei is among the most well-studied nearby binary star systems. Results of its observation have been applied to a wide range of fundamental studies of binary systems and stellar astrophysics. It is widely used to calibrate and constrain theoretical models of the physics of stars. We report 27 high precision differential astrometry measurements of delta Equulei from the Palomar High-precision Astrometric Search for Exoplanet Systems (PHASES). The median size of the minor axes of the uncertainty ellipses for these measurements is 26 micro-arcseconds. These data are combined with previously published radial velocity data and other previously published differential astrometry measurements using other techniques to produce a combined model for the system orbit. The distance to the system is determined to within a twentieth of a parsec and the component masses are determined at the level of a percent. The constraints on masses and distance are limited by the precisions of the radial velocity data; we outline plans improve this deficiency and discuss the outlook for further study of this binary.Comment: Accepted by AJ. Complete versions of tables 2-7 now available at http://stuff.mit.edu/~matthew1/deltaEquTables/ (removed from astroph server

Two-photon Lithography for 3D Magnetic Nanostructure Fabrication

Ferromagnetic materials have been utilised as recording media within data storage devices for many decades. Confinement of the material to a two dimensional plane is a significant bottleneck in achieving ultra-high recording densities and this has led to the proposition of three dimensional (3D) racetrack memories that utilise domain wall propagation along nanowires. However, the fabrication of 3D magnetic nanostructures of complex geometry is highly challenging and not easily achievable with standard lithography techniques. Here, by using a combination of two-photon lithography and electrochemical deposition, we show a new approach to construct 3D magnetic nanostructures of complex geometry. The magnetic properties are found to be intimately related to the 3D geometry of the structure and magnetic imaging experiments provide evidence of domain wall pinning at a 3D nanostructured junction

Interplay and Characterization of Dark Matter Searches at Colliders and in Direct Detection Experiments

In this White Paper we present and discuss a concrete proposal for the consistent interpretation of Dark Matter searches at colliders and in direct detection experiments. Based on a specific implementation of simplified models of vector and axial-vector mediator exchanges, this proposal demonstrates how the two search strategies can be compared on an equal footing

Lorentz and CPT Violation in Neutrinos

A general formalism is presented for violations of Lorentz and CPT symmetry in the neutrino sector. The effective hamiltonian for neutrino propagation in the presence of Lorentz and CPT violation is derived, and its properties are studied. Possible definitive signals in existing and future neutrino-oscillation experiments are discussed. Among the predictions are direction-dependent effects, including neutrino-antineutrino mixing, sidereal and annual variations, and compass asymmetries. Other consequences of Lorentz and CPT violation involve unconventional energy dependences in oscillation lengths and mixing angles. A variety of simple models both with and without neutrino masses are developed to illustrate key physical effects. The attainable sensitivities to coefficients for Lorentz violation in the Standard-Model Extension are estimated for various types of experiments. Many experiments have potential sensitivity to Planck-suppressed effects, comparable to the best tests in other sectors. The lack of existing experimental constraints, the wide range of available coefficient space, and the variety of novel effects imply that some or perhaps even all of the existing data on neutrino oscillations might be due to Lorentz and CPT violation.Comment: 25 pages REVTe

High-potency ligands for DREADD imaging and activation in rodents and monkeys

Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are a popular chemogenetic technology for manipulation of neuronal activity in uninstrumented awake animals with potential for human applications as well. The prototypical DREADD agonist clozapine N-oxide (CNO) lacks brain entry and converts to clozapine, making it difficult to apply in basic and translational applications. Here we report the development of two novel DREADD agonists, JHU37152 and JHU37160, and the first dedicated 18F positron emission tomography (PET) DREADD radiotracer, [18F]JHU37107. We show that JHU37152 and JHU37160 exhibit high in vivo DREADD potency. [18F]JHU37107 combined with PET allows for DREADD detection in locally-targeted neurons, and at their long-range projections, enabling noninvasive and longitudinal neuronal projection mapping

Whole exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer

Comprehensive analyses of cancer genomes promise to inform prognoses and precise cancer treatments. A major barrier, however, is inaccessibility of metastatic tissue. A potential solution is to characterize circulating tumor cells (CTCs), but this requires overcoming the challenges of isolating rare cells and sequencing low-input material. Here we report an integrated process to isolate, qualify and sequence whole exomes of CTCs with high fidelity, using a census-based sequencing strategy. Power calculations suggest that mapping of >99.995% of the standard exome is possible in CTCs. We validated our process in two prostate cancer patients including one for whom we sequenced CTCs, a lymph node metastasis and nine cores of the primary tumor. Fifty-one of 73 CTC mutations (70%) were observed in matched tissue. Moreover, we identified 10 early-trunk and 56 metastatic-trunk mutations in the non-CTC tumor samples and found 90% and 73% of these, respectively, in CTC exomes. This study establishes a foundation for CTC genomics in the clinic